Somatostatin receptor
| somatostatin receptor 1 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | SSTR1 | ||||||
| NCBI gene | 6751 | ||||||
| HGNC | 11330 | ||||||
| OMIM | 182451 | ||||||
| RefSeq | NM_001049 | ||||||
| UniProt | P30872 | ||||||
| Other data | |||||||
| Locus | Chr. 14 q13 | ||||||
| |||||||
| somatostatin receptor 2 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | SSTR2 | ||||||
| NCBI gene | 6752 | ||||||
| HGNC | 11331 | ||||||
| OMIM | 182452 | ||||||
| RefSeq | NM_001050 | ||||||
| UniProt | P30874 | ||||||
| Other data | |||||||
| Locus | Chr. 17 q24 | ||||||
| |||||||
| somatostatin receptor 3 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | SSTR3 | ||||||
| NCBI gene | 6753 | ||||||
| HGNC | 11332 | ||||||
| OMIM | 182453 | ||||||
| RefSeq | NM_001051 | ||||||
| UniProt | P32745 | ||||||
| Other data | |||||||
| Locus | Chr. 22 q13.1 | ||||||
| |||||||
| somatostatin receptor 4 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | SSTR4 | ||||||
| NCBI gene | 6754 | ||||||
| HGNC | 11333 | ||||||
| OMIM | 182454 | ||||||
| RefSeq | NM_001052 | ||||||
| UniProt | P31391 | ||||||
| Other data | |||||||
| Locus | Chr. 20 p11.2 | ||||||
| |||||||
| somatostatin receptor 5 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | SSTR5 | ||||||
| NCBI gene | 6755 | ||||||
| HGNC | 11334 | ||||||
| OMIM | 182455 | ||||||
| RefSeq | NM_001053 | ||||||
| UniProt | P35346 | ||||||
| Other data | |||||||
| Locus | Chr. 16 p13.3 | ||||||
| |||||||
Somatostatin receptors are receptors for the ligand somatostatin, a small neuropeptide associated with neural signaling, particularly in the post-synaptic response to NMDA receptor co-stimulation/activation. Somatostatin is encoded by a CRE and is very susceptible to gene promoter region activation by transcription factor CREB.
There are five known somatostatin receptors: