Soo Line Building
| First National Bank-Soo  Line Building | |
| Minneapolis Landmark | |
| Northwest view of the Soo Line Building (501 Marquette), 2005 | |
| Location | Minneapolis, Minnesota | 
|---|---|
| Coordinates | 44°58′41″N 93°16′9″W / 44.97806°N 93.26917°W | 
| Built | 1915 | 
| Architect | Robert W. Gibson | 
| NRHP reference No. | 08000402 | 
| Significant dates | |
| Added to NRHP | May 12, 2008 | 
| Designated MPLSL | 1996 | 
The Soo Line Building is a 19-story residential highrise in Minneapolis, Minnesota which was the tallest commercial building in the city from the time it was completed in 1915 until the 26-story Foshay Tower was built in 1929.