South Carolina Highway 381
| Route information | ||||
|---|---|---|---|---|
| Maintained by SCDOT | ||||
| Length | 22.700 mi (36.532 km) | |||
| Existed | 1930–present | |||
| Major junctions | ||||
| South end | SC 38 in Blenheim | |||
| US 15 / US 401 in McColl | ||||
| North end | NC 381 at the North Carolina line near Gibson, NC | |||
| Location | ||||
| Country | United States | |||
| State | South Carolina | |||
| Counties | Marlboro | |||
| Highway system | ||||
| ||||
South Carolina Highway 381 (SC 381) is a 22.700-mile (36.532 km) primary state highway in the U.S. state of South Carolina. It connects the towns in eastern Marlboro County.