Spatial biology

Spatial biology is the study of biomolecules and cells in their native three-dimensional context. Spatial biology encompasses different levels of cellular resolution including (1) subcellular localization of DNA, RNA, and proteins, (2) single-cell resolution and in situ communications like cell-cell interactions and cell signaling, (3) cellular neighborhoods, regions, or microenvironments, and (4) tissue architecture and organization in organs. Dysregulation of tissue organization is a common feature in human disease progression including tumorigenesis and neurodegeneration. Many fields within biology are studied for their individual contribution to spatial biology.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.