Steroid sulfatase

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Steryl-sulfatase
Steryl-sulfatase
Identifiers
EC no.	3.1.6.2
CAS no.	9025-62-1
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
PMC
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PubMed	articles
NCBI	proteins

STS
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	1P49
Identifiers
Aliases	STS, ARSC, ARSC2, ARSC1, ASC, ES, SSDD, XLI, Steroid sulfatase (microsomal), isozyme S, steroid sulfatase
External IDs	OMIM: 300747; HomoloGene: 47918; GeneCards: STS; OMA:STS - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	7,804,358 bp
RNA expression pattern
	Top expressed in
	placenta; ; endothelial cell; ; palpebral conjunctiva; ; Brodmann area 23; ; pancreatic ductal cell; ; decidua; ; lateral nuclear group of thalamus; ; middle temporal gyrus; ; primary visual cortex; ; Brodmann area 46;
	n/a
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	metal ion binding; catalytic activity; steryl-sulfatase activity; sulfuric ester hydrolase activity; hydrolase activity; arylsulfatase activity;
Cellular component	integral component of membrane; endosome; Golgi apparatus; endoplasmic reticulum lumen; membrane; endoplasmic reticulum membrane; plasma membrane; endoplasmic reticulum; lysosome; intracellular membrane-bounded organelle;
Biological process	steroid metabolic process; glycosphingolipid metabolic process; lipid metabolism; female pregnancy; steroid catabolic process; epidermis development; metabolism;
	Sources:Amigo / QuickGO
Orthologs
	412
	n/a
	ENSG00000101846
	n/a
	P08842
	n/a
NM_000351; NM_001320750; NM_001320751; NM_001320752; NM_001320753;
	NM_001320754
	n/a
NP_000342; NP_001307679; NP_001307680; NP_001307681; NP_001307682;
	NP_001307683
	n/a
	Wikidata
View/Edit Human

Steroid sulfatase (STS), or steryl-sulfatase (EC 3.1.6.2), formerly known as arylsulfatase C, is a sulfatase enzyme involved in the metabolism of steroids. It is encoded by the STS gene.