Steroidogenic acute regulatory protein
| steroidogenic acute regulatory protein | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | StAR | ||||||
| NCBI gene | 6770 | ||||||
| HGNC | 11359 | ||||||
| OMIM | 600617 | ||||||
| RefSeq | NM_000349 | ||||||
| UniProt | P49675 | ||||||
| Other data | |||||||
| Locus | Chr. 8 p11.2 | ||||||
| |||||||
The steroidogenic acute regulatory protein, commonly referred to as StAR (STARD1), is a transport protein that regulates cholesterol transfer within the mitochondria, which is the rate-limiting step in the production of steroid hormones. It is primarily present in steroid-producing cells, including theca cells and luteal cells in the ovary, Leydig cells in the testis and cell types in the adrenal cortex.