Suritozole

Suritozole
Clinical data
ATC code	none;
Identifiers
	IUPAC name 5-(3-fluorophenyl)-2,4-dimethyl-2,4-dihydro-3H-1,2,4-triazole-3-thione;
CAS Number	110623-33-1 ;
PubChem CID	25431;
ChemSpider	23743 ;
UNII	3H7H68317X;
KEGG	D05980 ;
CompTox Dashboard (EPA)	DTXSID10149333 ;
Chemical and physical data
Formula	C10H10FN3S
Molar mass	223.27 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Cn1c(=S)n(C)nc1-c2cccc(F)c2;
	InChI InChI=1S/C10H10FN3S/c1-13-9(12-14(2)10(13)15)7-4-3-5-8(11)6-7/h3-6H,1-2H3 ; Key:IWDUZEHNLHFBRZ-UHFFFAOYSA-N ;
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Suritozole (MDL 26,479) is an investigational cognition enhancer. It acts as a partial inverse agonist at the benzodiazepine receptor site on the GABA_A ion channel complex, but does not have either anxiogenic or convulsant effects, unlike other BZD inverse agonists such as DMCM. It was investigated for the treatment of depression and Alzheimer's disease in the 90s, but clinical development seems to have been discontinued.

Clinical data

ATC code	none
Identifiers
IUPAC name 5-(3-fluorophenyl)-2,4-dimethyl-2,4-dihydro-3H-1,2,4-triazole-3-thione
CAS Number	110623-33-1^Y
PubChem CID	25431
ChemSpider	23743^N
UNII	3H7H68317X
KEGG	D05980^Y
CompTox Dashboard (EPA)	DTXSID10149333
Chemical and physical data
Formula	C₁₀H₁₀FN₃S
Molar mass	223.27 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES Cn1c(=S)n(C)nc1-c2cccc(F)c2
InChI InChI=1S/C10H10FN3S/c1-13-9(12-14(2)10(13)15)7-4-3-5-8(11)6-7/h3-6H,1-2H3^N Key:IWDUZEHNLHFBRZ-UHFFFAOYSA-N^N
^NY (what is this?) (verify)