Swyer–James syndrome

Swyer–James syndrome
Other namesSwyer–James–Macleod's syndrome
Swyer–James syndrome of the left (smaller) lung, virtual CT-bronchography
SpecialtyPulmonology
SymptomsOften no symptoms, sometimes shortness of breath on exertion, wheeze, reduced ability to exercise, cough, chest pain
CausesChildhood bronchiolitis obliterans
Diagnostic methodmedical imaging
TreatmentBronchodilators
FrequencyRare

Swyer–James syndrome (SJS), also called Swyer–James–MacLeod syndrome, is a rare disease of the lungs, characterized by a small lung or part of lung. Typical symptoms are of recurrent respiratory tract infections, but some have no symptoms.

As a result of childhood bronchiolitis obliterans, typically following adenovirus infection, there is a reduction in blood vessels and overextended alveoli, resulting in air trapping in one or part of one lung.