Synaptophysin

SYP
Identifiers
Aliases	SYP, MRX96, MRXsynaptophysin, XLID96
External IDs	OMIM: 313475; MGI: 98467; HomoloGene: 2391; GeneCards: SYP; OMA:SYP - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	49,200,218 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	7,519,495 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; right frontal lobe; ; prefrontal cortex; ; Brodmann area 9; ; anterior cingulate cortex; ; Amygdala; ; anterior pituitary; ; Brodmann area 10; ; nucleus accumbens; ; C1 segment;
	Top expressed in
	neural layer of retina; ; dentate gyrus of hippocampal formation granule cell; ; medial dorsal nucleus; ; superior frontal gyrus; ; subiculum; ; cerebellar cortex; ; medial geniculate nucleus; ; dorsomedial hypothalamic nucleus; ; medial vestibular nucleus; ; habenula;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	SH2 domain binding; protein self-association; cholesterol binding; identical protein binding; syntaxin-1 binding;
Cellular component	integral component of membrane; membrane; synaptic vesicle; synapse; excitatory synapse; synaptic vesicle membrane; presynaptic active zone; cell junction; terminal bouton; integral component of synaptic vesicle membrane; neuron projection; neuron projection terminus; presynaptic membrane; cytoplasmic vesicle; neuromuscular junction; Schaffer collateral - CA1 synapse; perinuclear region of cytoplasm;
Biological process	cellular response to organic substance; regulation of long-term neuronal synaptic plasticity; endocytosis; regulation of opioid receptor signaling pathway; regulation of short-term neuronal synaptic plasticity; synaptic vesicle membrane organization; regulation of neuronal synaptic plasticity; synaptic vesicle maturation; synaptic vesicle endocytosis; regulation of synaptic vesicle exocytosis;
	Sources:Amigo / QuickGO
Orthologs
	6855
	20977
	ENSG00000102003
	ENSMUSG00000031144
	P08247
	Q62277
	NM_003179
	NM_009305
	NP_003170
	NP_033331
	Wikidata
View/Edit Human	View/Edit Mouse

Synaptophysin, also known as the major synaptic vesicle protein p38, is a protein that in humans is encoded by the SYP gene.