MAP3K7IP3

TAB3
Identifiers
Aliases	TAB3, MAP3K7IP3, NAP1, TGF-beta activated kinase 1/MAP3K7 binding protein 3, TGF-beta activated kinase 1 and MAP3K7 binding protein 3, TGF-beta activated kinase 1 (MAP3K7) binding protein 3
External IDs	OMIM: 300480; MGI: 1913974; HomoloGene: 17673; GeneCards: TAB3; OMA:TAB3 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	30,975,084 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	85,634,469 bp
RNA expression pattern
	Top expressed in
	pancreatic epithelial cell; ; pancreatic ductal cell; ; germinal epithelium; ; amniotic fluid; ; epithelium of nasopharynx; ; buccal mucosa cell; ; gingival epithelium; ; tail of epididymis; ; palpebral conjunctiva; ; visceral pleura;
	Top expressed in
	retinal pigment epithelium; ; ureter; ; facial motor nucleus; ; primitive streak; ; medullary collecting duct; ; blood; ; hair follicle; ; Paneth cell; ; fetal liver hematopoietic progenitor cell; ; sexually immature organism;
	More reference expression data
	n/a
Gene ontology
Molecular function	metal ion binding; protein binding;
Cellular component	cytosol; plasma membrane; endosome membrane; extracellular exosome;
Biological process	stimulatory C-type lectin receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; Fc-epsilon receptor signaling pathway; JNK cascade; positive regulation of NF-kappaB transcription factor activity; I-kappaB kinase/NF-kappaB signaling; negative regulation of autophagy; nucleotide-binding oligomerization domain containing signaling pathway; MyD88-independent toll-like receptor signaling pathway; positive regulation of I-kappaB kinase/NF-kappaB signaling; interleukin-1-mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	257397
	66724
	ENSG00000157625
	ENSMUSG00000035476
	Q8N5C8
	Q571K4
	NM_152787; NM_198312; NM_001399870; NM_001399872; NM_001399873
	NM_025729; NM_001358447
	NP_690000
	NP_080005; NP_001345376
	Wikidata
View/Edit Human	View/Edit Mouse

Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 is an enzyme that in humans is encoded by the MAP3K7IP3 gene.