TACC3

TACC3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4LPZ, 4PKY
Identifiers
Aliases	TACC3, ERIC-1, ERIC1, transforming acidic coiled-coil containing protein 3, Tacc4, maskin
External IDs	OMIM: 605303; MGI: 1341163; HomoloGene: 81618; GeneCards: TACC3; OMA:TACC3 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	1,745,171 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	33,678,995 bp
RNA expression pattern
	Top expressed in
	oocyte; ; ventricular zone; ; secondary oocyte; ; right testis; ; left testis; ; granulocyte; ; monocyte; ; blood; ; ganglionic eminence; ; gonad;
	Top expressed in
	primary oocyte; ; ventricular zone; ; yolk sac; ; epiblast; ; tail of embryo; ; primitive streak; ; spermatocyte; ; genital tubercle; ; maxillary prominence; ; embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	cytoplasm; microtubule cytoskeleton; spindle pole; spindle; cytoskeleton; microtubule organizing center; cytosol; mitotic spindle;
Biological process	cell population proliferation; cerebral cortex development; metaphase; regulation of mitotic spindle organization; microtubule cytoskeleton organization involved in mitosis; cell cycle; cell division; microtubule cytoskeleton organization; mitotic spindle organization;
	Sources:Amigo / QuickGO
Orthologs
	10460
	21335
	ENSG00000013810
	ENSMUSG00000037313
	Q9Y6A5
	Q9JJ11
	NM_006342
	NM_001040435; NM_011524; NM_001310541
	NP_006333
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Transforming acidic coiled-coil-containing protein 3 is a protein that in humans is encoded by the TACC3 gene.

The function of this gene has not yet been determined; however, it is speculated that it may be involved in cell growth and differentiation. Expression of this gene is up-regulated in some cancer cell lines, and in embryonic day 15 in mice.