TAF1

TAF1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1EQF, 3AAD, 3UV4, 3UV5, 4RGW, 4YYM, 4YYN, 5I29, 5I1Q, 5FUR
Identifiers
Aliases	TAF1, BA2R, CCG1, CCGS, DYT3, DYT3/KAT4, N-NSCL2, OF, P250, TAF(II)250, TAF2A, TAFII-250, TAFII250, XDP, MRXS33, TATA-box binding protein associated factor 1
External IDs	OMIM: 313650; MGI: 1336878; HomoloGene: 37942; GeneCards: TAF1; OMA:TAF1 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	71,532,374 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	100,645,395 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; Achilles tendon; ; epithelium of colon; ; urethra; ; tonsil; ; left ovary; ; lactiferous duct; ; pericardium; ; corpus callosum; ; body of uterus;
	Top expressed in
	hand; ; neural layer of retina; ; dentate gyrus of hippocampal formation granule cell; ; Gonadal ridge; ; Rostral migratory stream; ; ventricular zone; ; maxillary prominence; ; ventral tegmental area; ; tail of embryo; ; arcuate nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; DNA binding; transcription coactivator activity; p53 binding; transcription factor binding; protein binding; lysine-acetylated histone binding; TBP-class protein binding; acyltransferase activity; ATP binding; protein serine/threonine kinase activity; histone acetyltransferase activity; kinase activity; protein heterodimerization activity; H3K27me3 modified histone binding; ubiquitin conjugating enzyme activity; acetyl-CoA binding; sequence-specific DNA binding; RNA polymerase II core promoter sequence-specific DNA binding; RNA polymerase II-specific DNA-binding transcription factor binding; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II general transcription initiation factor activity;
Cellular component	nucleoplasm; MLL1 complex; nucleus; nucleolus; transcription regulator complex; transcription factor TFIID complex;
Biological process	phosphorylation; RNA polymerase II preinitiation complex assembly; transcription by RNA polymerase II; positive regulation of transcription initiation from RNA polymerase II promoter; transcription, DNA-templated; peptidyl-serine phosphorylation; DNA-templated transcription, initiation; protein autophosphorylation; cell cycle; transcription initiation from RNA polymerase II promoter; peptidyl-threonine phosphorylation; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of transcription by RNA polymerase II; regulation of signal transduction by p53 class mediator; viral process; histone acetylation; protein polyubiquitination; protein phosphorylation; cellular response to DNA damage stimulus; negative regulation of gene expression; midbrain development; positive regulation of protein binding; cellular response to UV; transcription factor catabolic process; protein stabilization; regulation of transcription initiation from RNA polymerase II promoter; cellular response to ATP; regulation of cell cycle G1/S phase transition; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding; negative regulation of protein autoubiquitination; negative regulation of ubiquitin-dependent protein catabolic process; positive regulation of androgen receptor activity; positive regulation of transcription by RNA polymerase I; regulation of transcription, DNA-templated; negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage; negative regulation of DNA-binding transcription factor activity; ubiquitin-dependent protein catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	6872
	270627
	ENSG00000147133
	ENSMUSG00000031314
	P21675
	Q80UV9
	NM_001286074; NM_004606; NM_138923
	NM_001081008; NM_001290729
	NP_001273003; NP_004597; NP_620278
	NP_001277658; NP_001392888; NP_001392889; NP_001392890; NP_001392891
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription initiation factor TFIID subunit 1, also known as transcription initiation factor TFIID 250 kDa subunit (TAFII-250) or TBP-associated factor 250 kDa (p250), is a protein that in humans is encoded by the TAF1 gene.