TAOK1

TAOK1
Identifiers
Aliases	TAOK1, KFC-B, MAP3K16, MARKK, PSK-2, PSK2, TAO1, hKFC-B, hTAO kinase 1, DDIB
External IDs	OMIM: 610266; MGI: 1914490; HomoloGene: 27041; GeneCards: TAOK1; OMA:TAOK1 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	29,551,903 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	77,498,641 bp
RNA expression pattern
	Top expressed in
	corpus callosum; ; globus pallidus; ; internal globus pallidus; ; ventral tegmental area; ; subthalamic nucleus; ; sural nerve; ; pars compacta; ; inferior ganglion of vagus nerve; ; Pons; ; external globus pallidus;
	Top expressed in
	ventromedial nucleus; ; lateral septal nucleus; ; Amygdala; ; lateral geniculate nucleus; ; olfactory tubercle; ; anterior amygdaloid area; ; mammillary body; ; habenula; ; inferior colliculi; ; globus pallidus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; protein kinase activity; nucleotide binding; kinase activity; protein serine/threonine kinase activity; protein binding; ATP binding; MAP kinase kinase kinase activity; alpha-tubulin binding; protein serine/threonine kinase activator activity; tau protein binding; beta-tubulin binding; tau-protein kinase activity;
Cellular component	cytoplasm; cytosol; extracellular exosome; nucleus; microtubule cytoskeleton; perinuclear region of cytoplasm;
Biological process	phosphorylation; execution phase of apoptosis; positive regulation of JNK cascade; cellular response to DNA damage stimulus; protein phosphorylation; spindle checkpoint signaling; regulation of cytoskeleton organization; DNA repair; positive regulation of stress-activated MAPK cascade; apoptotic process; sister chromatid cohesion; MAPK cascade; regulation of mitotic cell cycle; nervous system development; regulation of apoptotic process; microtubule cytoskeleton organization; negative regulation of microtubule depolymerization; mitotic G2 DNA damage checkpoint signaling; signal transduction; stress-activated protein kinase signaling cascade; activation of protein kinase activity; regulation of actin cytoskeleton organization; protein autophosphorylation; neuron cellular homeostasis; regulation of microtubule cytoskeleton organization; positive regulation of protein acetylation;
	Sources:Amigo / QuickGO
Orthologs
	57551
	216965
	ENSG00000160551
	ENSMUSG00000017291
	Q7L7X3
	Q5F2E8
	NM_020791; NM_025142
	NM_144825; NM_001364133; NM_001364134
	NP_065842; NP_079418
	NP_659074; NP_001351062; NP_001351063
	Wikidata
View/Edit Human	View/Edit Mouse

Serine/threonine-protein kinase TAO1 is an enzyme that in humans is encoded by the TAOK1 gene.