Tapasin

TAPBP
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3F8U
Identifiers
Aliases	TAPBP, NGS17, TAPA, TPN, TPSN, TAP binding protein (tapasin), TAP binding protein
External IDs	OMIM: 601962; MGI: 1201689; HomoloGene: 2401; GeneCards: TAPBP; OMA:TAPBP - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	33,314,254 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	34,148,266 bp
RNA expression pattern
	Top expressed in
	bone marrow cells; ; granulocyte; ; blood; ; spleen; ; mucosa of transverse colon; ; monocyte; ; appendix; ; lymph node; ; epithelium of colon; ; right adrenal gland;
	Top expressed in
	mesenteric lymph nodes; ; Ileal epithelium; ; subcutaneous adipose tissue; ; blood; ; stroma of bone marrow; ; right lung; ; spleen; ; right lung lobe; ; pituitary gland; ; submandibular gland;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	peptide antigen binding; TAP2 binding; unfolded protein binding; ABC-type peptide antigen transporter activity; protein binding; MHC class I protein binding; TAP1 binding; TAP complex binding;
Cellular component	integral component of membrane; endoplasmic reticulum membrane; membrane; Golgi membrane; TAP complex; MHC class I peptide loading complex; endoplasmic reticulum; integral component of lumenal side of endoplasmic reticulum membrane; phagocytic vesicle membrane; endoplasmic reticulum-Golgi intermediate compartment membrane;
Biological process	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; antigen processing and presentation of peptide antigen via MHC class I; antigen processing and presentation of endogenous peptide antigen via MHC class I; regulation of protein complex stability; immune response; peptide antigen stabilization; regulation of gene expression; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane; amide transport; protein-containing complex assembly; MHC class Ib protein complex assembly; peptide transport;
	Sources:Amigo / QuickGO
Orthologs
	6892
	21356
ENSG00000231925; ENSG00000236490; ENSG00000206281; ENSG00000206208; ENSG00000112493;
	n/a
	ENSMUSG00000024308
	O15533
	Q9R233
	NM_003190; NM_172208; NM_172209
	NM_001025313; NM_009318
	NP_003181; NP_757345; NP_757346
	NP_001020484; NP_033344
	Wikidata
View/Edit Human	View/Edit Mouse

TAP-associated glycoprotein, also known as tapasin or TAPBP, is a protein that in humans is encoded by the TAPBP gene.