TAS1R3

TAS1R3
Identifiers
Aliases	TAS1R3, T1R3, taste 1 receptor member 3
External IDs	OMIM: 605865; MGI: 1933547; HomoloGene: 12890; GeneCards: TAS1R3; OMA:TAS1R3 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	1,335,314 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	155,947,819 bp
RNA expression pattern
	Top expressed in
	bone marrow cells; ; mucosa of transverse colon; ; spleen; ; tonsil; ; duodenum; ; lymph node; ; ganglionic eminence; ; muscle of thigh; ; sural nerve; ; gastrocnemius muscle;
	Top expressed in
	ascending aorta; ; aortic valve; ; morula; ; granulocyte; ; tongue; ; tail of embryo; ; supraoptic nucleus; ; ganglionic eminence; ; esophagus; ; jejunum;
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity; taste receptor activity; protein heterodimerization activity; sweet taste receptor activity; signaling receptor activity;
Cellular component	integral component of membrane; plasma membrane; sweet taste receptor complex; membrane; integral component of plasma membrane;
Biological process	sensory perception of taste; sensory perception of sweet taste; sensory perception of umami taste; detection of chemical stimulus involved in sensory perception of sweet taste; signal transduction; response to stimulus; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	83756
	83771
	ENSG00000169962
	ENSMUSG00000029072
	Q7RTX0
	Q925D8
	NM_152228
	NM_031872
	NP_689414
	NP_114078
	Wikidata
View/Edit Human	View/Edit Mouse

Taste receptor type 1 member 3 is a protein that in humans is encoded by the TAS1R3 gene. The TAS1R3 gene encodes the human homolog of mouse Sac taste receptor, a major determinant of differences between sweet-sensitive and -insensitive mouse strains in their responsiveness to sucrose, saccharin, and other sweeteners.