TAS2R38

TAS2R38
Identifiers
Aliases	TAS2R38, PTC, T2R38, T2R61, taste 2 receptor member 38, THIOT
External IDs	OMIM: 607751; MGI: 2681306; HomoloGene: 47976; GeneCards: TAS2R38; OMA:TAS2R38 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	141,973,773 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	40,590,244 bp
RNA expression pattern
	Top expressed in
	rectum; ; mucosa of transverse colon; ; sural nerve; ; duodenum; ; placenta; ; mucosa of small intestine; ; smooth muscle tissue; ; male reproductive gland; ; prostate;
	Top expressed in
	proximal tubule;
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity; bitter taste receptor activity;
Cellular component	membrane; plasma membrane; integral component of membrane;
Biological process	detection of chemical stimulus involved in sensory perception of bitter taste; signal transduction; response to stimulus; sensory perception of taste; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	5726
	387513
	ENSG00000257138
	ENSMUSG00000058250
	P59533
	Q7TQA6
	NM_176817
	NM_001001451
	NP_789787
	NP_001001451
	Wikidata
View/Edit Human	View/Edit Mouse

Taste receptor 2 member 38 is a protein that in humans is encoded by the TAS2R38 gene. TAS2R38 is a bitter taste receptor; varying genotypes of TAS2R38 influence the ability to taste both 6-n-propylthiouracil (PROP) and phenylthiocarbamide (PTC). Though it has often been proposed that varying taste receptor genotypes could influence tasting ability, TAS2R38 is one of the few taste receptors shown to have this function.