TBX6

TBX6
Identifiers
Aliases	TBX6, SCDO5, T-box 6, T-box transcription factor 6
External IDs	OMIM: 602427; MGI: 102539; HomoloGene: 3389; GeneCards: TBX6; OMA:TBX6 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	30,091,924 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	126,384,732 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; pancreatic ductal cell; ; olfactory zone of nasal mucosa; ; vagina; ; deltoid muscle; ; tibialis anterior muscle; ; mucosa of ileum; ; body of pancreas; ; granulocyte; ; skin of abdomen;
	Top expressed in
	tail of embryo; ; paraxial mesoderm; ; granulocyte; ; primitive streak; ; female urethra; ; embryo; ; male urethra; ; mesoderm; ; Ileal epithelium; ; embryo;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA-binding transcription factor activity; DNA binding; protein binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus;
Biological process	cell fate specification; multicellular organism development; somite rostral/caudal axis specification; mesoderm formation; anatomical structure morphogenesis; negative regulation of neuron maturation; mesoderm development; signal transduction involved in regulation of gene expression; negative regulation of neuron projection development; regulation of transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; negative regulation of DNA-binding transcription factor activity;
	Sources:Amigo / QuickGO
Orthologs
	6911
	21389
	ENSG00000149922
	ENSMUSG00000030699
	O95947
	P70327
	NM_004608; NM_080758
	NM_011538
	NP_004599
	NP_035668
	Wikidata
View/Edit Human	View/Edit Mouse

T-box 6 is a protein that in humans is encoded by the TBX6 gene.