TCF20

TCF20
Identifiers
Aliases	TCF20, AR1, SPBP, TCF-20, transcription factor 20 (AR1), transcription factor 20, DDVIBA
External IDs	OMIM: 603107; MGI: 108399; HomoloGene: 4131; GeneCards: TCF20; OMA:TCF20 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	42,343,616 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	82,872,073 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; bone marrow cells; ; islet of Langerhans; ; tonsil; ; mucosa of esophagus; ; blood; ; granulocyte; ; lymph node; ; olfactory zone of nasal mucosa; ; superior frontal gyrus;
	Top expressed in
	Rostral migratory stream; ; genital tubercle; ; tail of embryo; ; dentate gyrus of hippocampal formation granule cell; ; secondary oocyte; ; olfactory tubercle; ; ciliary body; ; dorsal striatum; ; conjunctival fornix; ; supraoptic nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; transcription coactivator activity; metal ion binding; RNA binding; DNA-binding transcription factor activity; protein binding;
Cellular component	nucleoplasm; nuclear body; nucleus;
Biological process	regulation of transcription, DNA-templated; transcription, DNA-templated; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	6942
	21411
ENSG00000283681; ENSG00000281897; ENSG00000262024; ENSG00000282892; ENSG00000283026;
	ENSG00000280467; ENSG00000100207; ENSG00000276461
	ENSMUSG00000041852
	Q9UGU0
	Q9EPQ8
	NM_005650; NM_181492; NM_001378418
	NM_001114140; NM_013836
	NP_005641; NP_852469; NP_001365347
	NP_001107612; NP_038864; NP_001389767
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription factor 20 is a protein that in humans is encoded by the TCF20 gene.

The protein encoded by this gene binds a platelet-derived growth factor-responsive element in the matrix metalloproteinase 3 (stromelysin 1) promoter. The protein localizes to the nucleus and displays DNA-binding and transactivation activities. It is thought to be a transcriptional coactivator, enhancing the activity of transcription factors such as JUN and SP1. Alternative splicing results in two transcript variants encoding different isoforms.