TDIQ

TDIQ
Clinical data
Other names	6,7-Methylenedioxy-1,2,3,4-tetrahydroisoquinoline; 6,7-Methylenedioxy-THIQ; MDTHIQ; MDA-CR; "MDA-Conformationally Restricted"; MDA-THIQ; MDA/THIQ
Identifiers
	IUPAC name 5,6,7,8-Tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline;
CAS Number	15052-05-8 ;
PubChem CID	27013;
ChemSpider	25154;
UNII	N2NE2TM9ZF;
CompTox Dashboard (EPA)	DTXSID00933985 ;
Chemical and physical data
Formula	C10H11NO2
Molar mass	177.203 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES c23OCOc2cc1CCNCc1c3;
	InChI InChI=1S/C10H11NO2/c1-2-11-5-8-4-10-9(3-7(1)8)12-6-13-10/h3-4,11H,1-2,5-6H2; Key:JHLDJOBIUVJSTG-UHFFFAOYSA-N;
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TDIQ, also known as MDTHIQ or MDA-CR, is a tetrahydroisoquinoline drug used in scientific research, which has anxiolytic and anorectic effects in animals. It has an unusual effects profile in animals, with the effects generalising to cocaine and partially to MDMA and ephedrine, but the effects did not generalise to amphetamine and TDIQ does not have any stimulant effects. It is thought these effects are mediated via a partial agonist action at Alpha-2 adrenergic receptors, and TDIQ has been suggested as a possible drug for the treatment of cocaine dependence.