Testis-expressed protein 14

TEX14
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3WUT, 3WUU
Identifiers
Aliases	TEX14, CT113, testis expressed 14, intercellular bridge forming factor, SPGF23
External IDs	OMIM: 605792; MGI: 1933227; HomoloGene: 12838; GeneCards: TEX14; OMA:TEX14 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	58,692,055 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	87,446,649 bp
RNA expression pattern
	Top expressed in
	right testis; ; left testis; ; gonad; ; oocyte; ; secondary oocyte; ; testicle; ; sperm; ; cerebellar cortex; ; cerebellar hemisphere; ; right hemisphere of cerebellum;
	Top expressed in
	spermatocyte; ; spermatid; ; seminiferous tubule; ; zygote; ; Gonadal ridge; ; secondary oocyte; ; ovary; ; primary oocyte; ; cumulus cell; ; morula;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; nucleotide binding; protein kinase binding; protein kinase activity; ATP binding;
Cellular component	cytoplasm; chromosome; chromosome, centromeric region; extracellular exosome; intercellular bridge; midbody; kinetochore;
Biological process	cell cycle; negative regulation of cytokinesis; cell division; protein phosphorylation; negative regulation of protein binding; mitotic spindle assembly checkpoint signaling; male meiotic nuclear division; intercellular bridge organization; attachment of spindle microtubules to kinetochore; mitotic sister chromatid separation; cellular response to leukemia inhibitory factor;
	Sources:Amigo / QuickGO
Orthologs
	56155
	83560
	ENSG00000121101
	ENSMUSG00000010342
	Q8IWB6
	Q7M6U3
	NM_001201457; NM_031272; NM_198393
	NM_001199293; NM_031386
	NP_001188386; NP_112562; NP_938207
	NP_001186222; NP_113563
	Wikidata
View/Edit Human	View/Edit Mouse

Testis-expressed protein 14 is a protein in humans encoded by the TEX14 gene, and is 1497 amino acids in length. TEX14 plays a vital role in the formation of germ cells, as it is an essential component of the mammalian germ cell interphase bridge.

An orthologue of TEX14 exists in other mammals, also called TEX14.