TFAP2B

TFAP2B
Identifiers
Aliases	TFAP2B, AP-2B, AP2-B, transcription factor AP-2 beta, PDA2, AP-2beta
External IDs	OMIM: 601601; MGI: 104672; HomoloGene: 20688; GeneCards: TFAP2B; OMA:TFAP2B - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	50,847,619 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	19,308,800 bp
RNA expression pattern
	Top expressed in
	corpus epididymis; ; tail of epididymis; ; oocyte; ; secondary oocyte; ; parotid gland; ; buccal mucosa cell; ; palpebral conjunctiva; ; renal medulla; ; epithelium of lactiferous gland; ; lactiferous duct;
	Top expressed in
	neural layer of retina; ; connecting tubule; ; parotid gland; ; thin ascending limb of loop of Henle; ; hair follicle; ; superior cervical ganglion; ; maxillary prominence; ; conjunctival fornix; ; iris; ; lacrimal gland;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; transcription coactivator activity; sequence-specific DNA binding; transcription corepressor activity; protein dimerization activity; protein homodimerization activity; DNA-binding transcription factor activity; DNA-binding transcription activator activity, RNA polymerase II-specific; chromatin binding; RNA polymerase II general transcription initiation factor activity; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; protein binding; cis-regulatory region sequence-specific DNA binding; protein heterodimerization activity; RNA polymerase II core promoter sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding;
Cellular component	nucleus; nucleoplasm;
Biological process	negative regulation of neuron apoptotic process; forelimb morphogenesis; collecting duct development; cellular urea homeostasis; regulation of transcription, DNA-templated; sympathetic nervous system development; retina layer formation; positive regulation of urine volume; glucose homeostasis; calcium ion homeostasis; distal tubule development; kidney development; regulation of insulin secretion; phosphate ion homeostasis; cellular creatinine homeostasis; negative regulation of apoptotic process; transcription by RNA polymerase II; metanephric nephron development; aorta morphogenesis; magnesium ion homeostasis; hindlimb morphogenesis; transcription, DNA-templated; response to lithium ion; regulation of BMP signaling pathway; positive regulation of transcription, DNA-templated; positive regulation of neuron apoptotic process; cellular ammonium homeostasis; potassium ion homeostasis; positive regulation of cell population proliferation; renal water homeostasis; glucose metabolic process; sensory organ development; regulation of cell differentiation; sodium ion homeostasis; negative regulation of transcription, DNA-templated; fat cell differentiation; ductus arteriosus closure; negative regulation of cell population proliferation; skin development; apoptotic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	7021
	21419
	ENSG00000008196
	ENSMUSG00000025927
	Q92481
	Q61313
	NM_003221
	NM_001025305; NM_001286340; NM_009334
	NP_003212
	NP_001020476; NP_001273269; NP_033360
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription factor AP-2 beta also known as AP2-beta is a protein that in humans is encoded by the TFAP2B gene.