TFDP2

TFDP2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1CF7
Identifiers
Aliases	TFDP2, DP2, transcription factor Dp-2
External IDs	OMIM: 602160; MGI: 107167; HomoloGene: 4578; GeneCards: TFDP2; OMA:TFDP2 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	142,149,544 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	96,323,646 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; left testis; ; right testis; ; ventricular zone; ; bone marrow cells; ; thymus; ; ganglionic eminence; ; gonad; ; epithelium of colon; ; olfactory zone of nasal mucosa;
	Top expressed in
	blood; ; otic vesicle; ; myocardium of ventricle; ; tibialis anterior muscle; ; interventricular septum; ; hand; ; tail of embryo; ; vastus lateralis muscle; ; genital tubercle; ; Epithelium of choroid plexus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; DNA binding; transcription factor binding; protein binding; transcription coregulator activity; protein domain specific binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus; transcription regulator complex; nucleoplasm; mitochondrion; RNA polymerase II transcription regulator complex;
Biological process	regulation of transcription by RNA polymerase II; cell cycle; negative regulation of transcription, DNA-templated; regulation of transcription, DNA-templated; mitotic cell cycle; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; heart development; transcription, DNA-templated; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; regulation of transcription involved in G1/S transition of mitotic cell cycle; transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; negative regulation of G0 to G1 transition; regulation of cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	7029
	211586
	ENSG00000114126
	ENSMUSG00000032411
	Q14188
	Q64163
NM_001178138; NM_001178139; NM_001178140; NM_001178141; NM_001178142;
	NM_006286; NM_001375756; NM_001375773; NM_001375774; NM_001375775; NM_001375776; NM_001375778; NM_001375779; NM_001375780
NM_001184706; NM_001184708; NM_001184709; NM_001184710; NM_001184711;
	NM_178667
NP_001171609; NP_001171610; NP_001171611; NP_001171612; NP_001171613;
	NP_006277; NP_001362685; NP_001362702; NP_001362703; NP_001362704; NP_001362705; NP_001362707; NP_001362708; NP_001362709
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription factor Dp-2 is a protein that in humans is encoded by the TFDP2 gene that dimerises with E2F, a key transcriptional activator involved in the regulation of the cell cycle.