Trefoil factor 1

TFF1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1HI7, 1PS2
Identifiers
Aliases	TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2, trefoil factor 1
External IDs	OMIM: 113710; MGI: 88135; HomoloGene: 2426; GeneCards: TFF1; OMA:TFF1 - orthologs
Gene location (Human)
Chr.	Chromosome 21 (human)
End	42,366,535 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	31,384,251 bp
RNA expression pattern
	Top expressed in
	pancreatic ductal cell; ; gastric mucosa; ; palpebral conjunctiva; ; pylorus; ; mucosa of sigmoid colon; ; mucosa of ileum; ; gallbladder; ; cardia; ; rectum; ; jejunal mucosa;
	Top expressed in
	pyloric antrum; ; epithelium of stomach; ; mucous cell of stomach; ; tibiofemoral joint; ; perirhinal cortex; ; entorhinal cortex; ; right ventricle; ; CA3 field; ; Ileal epithelium; ; choroid plexus of fourth ventricle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	growth factor activity; protein binding;
Cellular component	extracellular space; extracellular region;
Biological process	response to immobilization stress; cell differentiation; response to peptide hormone; maintenance of gastrointestinal epithelium; negative regulation of cell population proliferation; response to iron ion; wound healing; carbohydrate metabolic process; regulation of signaling receptor activity; digestion; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	7031
	21784
	ENSG00000160182
	ENSMUSG00000024032
	P04155
	Q08423
	NM_003225
	NM_009362
	NP_003216
	NP_033388
	Wikidata
View/Edit Human	View/Edit Mouse

Trefoil factor 1 is a protein that in humans is encoded by the TFF1 gene (also called pS2 gene).