Keratinocyte transglutaminase

TGM1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2XZZ
Identifiers
Aliases	TGM1, ARCI1, ICR2, KTG, LI, LI1, TGASE, TGK, transglutaminase 1
External IDs	OMIM: 190195; MGI: 98730; HomoloGene: 306; GeneCards: TGM1; OMA:TGM1 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	24,264,432 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	55,951,383 bp
RNA expression pattern
	Top expressed in
	skin of leg; ; skin of abdomen; ; vagina; ; right hemisphere of cerebellum; ; testicle; ; tonsil; ; minor salivary glands; ; olfactory zone of nasal mucosa; ; ectocervix; ; gonad;
	Top expressed in
	esophagus; ; lip; ; yolk sac; ; right kidney; ; proximal tubule; ; skin of abdomen; ; skin of back; ; skin of external ear; ; epidermis; ; iris;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; acyltransferase activity; protein binding; metal ion binding; protein-glutamine gamma-glutamyltransferase activity;
Cellular component	intrinsic component of membrane; extracellular exosome; membrane; cornified envelope; cytosol; plasma membrane;
Biological process	cell envelope organization; keratinization; positive regulation of keratinocyte proliferation; positive regulation of cell cycle; keratinocyte differentiation; cornification; peptide cross-linking;
	Sources:Amigo / QuickGO
Orthologs
	7051
	21816
	ENSG00000092295; ENSG00000285348
	ENSMUSG00000022218
	P22735
	Q9JLF6
	NM_000359
	NM_001161714; NM_001161715; NM_019984
	NP_000350
	NP_001155186; NP_001155187; NP_064368
	Wikidata
View/Edit Human	View/Edit Mouse

Protein-glutamine gamma-glutamyltransferase K is a transglutaminase enzyme that in humans is encoded by the TGM1 gene.