TGS1

TGS1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3EGI, 3GDH
Identifiers
Aliases	TGS1, NCOA6IP, PIMT, PIPMT, trimethylguanosine synthase 1
External IDs	OMIM: 606461; MGI: 2151797; HomoloGene: 32608; GeneCards: TGS1; OMA:TGS1 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	55,826,445 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	3,616,619 bp
RNA expression pattern
	Top expressed in
	tendon of biceps brachii; ; oocyte; ; secondary oocyte; ; Achilles tendon; ; nipple; ; tail of epididymis; ; pylorus; ; internal globus pallidus; ; renal medulla; ; corpus epididymis;
	Top expressed in
	tail of embryo; ; condyle; ; cumulus cell; ; genital tubercle; ; ureter; ; primitive streak; ; pineal gland; ; renal corpuscle; ; fossa; ; abdominal wall;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	methyltransferase activity; transferase activity; RNA trimethylguanosine synthase activity; protein binding; RNA methyltransferase activity;
Cellular component	cytoplasm; Cajal body; nucleoplasm; nucleolus; small nuclear ribonucleoprotein complex; nucleus; extracellular space; cytosol;
Biological process	regulation of transcription, DNA-templated; transcription, DNA-templated; spliceosomal snRNP assembly; methylation; 7-methylguanosine RNA capping; 7-methylguanosine cap hypermethylation; ribonucleoprotein complex biogenesis; RNA methylation; regulation of lipid metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	96764
	116940
	ENSG00000137574
	ENSMUSG00000028233
	Q96RS0
	Q923W1
	NM_024831; NM_001317902; NM_001363184
	NM_054089
	NP_001304831; NP_079107; NP_001350113
	NP_473430
	Wikidata
View/Edit Human	View/Edit Mouse

Trimethylguanosine synthase is an enzyme that in humans is encoded by the TGS1 gene.