THOP1

THOP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1S4B, 2O36
Identifiers
Aliases	THOP1, EP24.15, MEPD_HUMAN, MP78, TOP, thimet oligopeptidase 1
External IDs	OMIM: 601117; MGI: 1354165; HomoloGene: 55726; GeneCards: THOP1; OMA:THOP1 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	2,815,807 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	80,918,393 bp
RNA expression pattern
	Top expressed in
	left testis; ; right testis; ; right hemisphere of cerebellum; ; right frontal lobe; ; ventricular zone; ; right lobe of liver; ; apex of heart; ; anterior pituitary; ; muscle of thigh; ; mucosa of transverse colon;
	Top expressed in
	spermatid; ; spermatocyte; ; esophagus; ; seminiferous tubule; ; lip; ; epiblast; ; tail of embryo; ; internal carotid artery; ; embryo; ; genital tubercle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	peptide binding; peptidase activity; hydrolase activity; metallopeptidase activity; metal ion binding; metalloendopeptidase activity;
Cellular component	cytoplasm; mitochondrial intermembrane space; cytosol;
Biological process	proteolysis; peptide metabolic process; protein polyubiquitination;
	Sources:Amigo / QuickGO
Orthologs
	7064
	50492
	ENSG00000172009
	ENSMUSG00000004929
	P52888
	Q8C1A5
	NM_003249
	NM_022653
	NP_003240
	NP_073144
	Wikidata
View/Edit Human	View/Edit Mouse

Thimet oligopeptidase is an enzyme that in humans is encoded by the THOP1 gene.