TLK2

TLK2
Identifiers
Aliases	TLK2, HsHPK, PKU-ALPHA, tousled like kinase 2, MRD57
External IDs	OMIM: 608439; MGI: 1346023; HomoloGene: 4993; GeneCards: TLK2; OMA:TLK2 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	62,615,481 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	105,174,785 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; sural nerve; ; epithelium of colon; ; bone marrow cells; ; ventricular zone; ; gonad; ; ganglionic eminence; ; left testis; ; right testis; ; stromal cell of endometrium;
	Top expressed in
	genital tubercle; ; tail of embryo; ; spermatocyte; ; neural layer of retina; ; zygote; ; secondary oocyte; ; seminiferous tubule; ; spermatid; ; ureter; ; ventricular zone;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein kinase activity; kinase activity; protein serine/threonine kinase activity; protein binding; ATP binding;
Cellular component	cytoplasm; perinuclear region of cytoplasm; cytoskeleton; intermediate filament; nucleus;
Biological process	intracellular signal transduction; phosphorylation; chromosome segregation; cellular response to DNA damage stimulus; protein phosphorylation; peptidyl-serine phosphorylation; cellular response to gamma radiation; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; cell cycle; negative regulation of autophagy; chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
	11011
	24086
	ENSG00000146872
	ENSMUSG00000020694
	Q86UE8
	O55047
NM_001112707; NM_001284333; NM_001284363; NM_006852; NM_001330418;
	NM_001375269; NM_001375270; NM_001375271; NM_001375272; NM_001375273
NM_001112705; NM_001294329; NM_001294330; NM_001294331; NM_001294334;
	NM_011903; NM_001361996
NP_001271262; NP_001271292; NP_001317347; NP_006843; NP_001362198;
	NP_001362199; NP_001362200; NP_001362201; NP_001362202
NP_001106176; NP_001281258; NP_001281259; NP_001281260; NP_001281263;
	NP_001348925
	Wikidata
View/Edit Human	View/Edit Mouse

Serine/threonine-protein kinase tousled-like 2 is an enzyme that in humans is encoded by the TLK2 gene.