TM7SF2

TM7SF2
Identifiers
Aliases	TM7SF2, ANG1, DHCR14A, NET47, transmembrane 7 superfamily member 2, C14SR
External IDs	OMIM: 603414; MGI: 1920416; HomoloGene: 68305; GeneCards: TM7SF2; OMA:TM7SF2 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	65,116,384 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	6,118,403 bp
RNA expression pattern
	Top expressed in
	right adrenal cortex; ; left adrenal cortex; ; body of pancreas; ; right lobe of liver; ; apex of heart; ; skin of abdomen; ; skin of leg; ; vulva; ; prefrontal cortex; ; left ovary;
	Top expressed in
	left lobe of liver; ; otic vesicle; ; ciliary body; ; spinal ganglia; ; otic placode; ; iris; ; esophagus; ; medial dorsal nucleus; ; neural layer of retina; ; pyloric antrum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	oxidoreductase activity, acting on the CH-CH group of donors; oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; oxidoreductase activity; delta14-sterol reductase activity; NADP binding;
Cellular component	organelle membrane; integral component of membrane; endoplasmic reticulum membrane; membrane; receptor complex; integral component of plasma membrane; integral component of endoplasmic reticulum membrane; nuclear inner membrane; endoplasmic reticulum; intracellular membrane-bounded organelle;
Biological process	steroid metabolic process; sterol biosynthetic process; lipid metabolism; cholesterol metabolic process; cholesterol biosynthetic process; steroid biosynthetic process; regulation of cholesterol biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	7108
	73166
	ENSG00000149809
	ENSMUSG00000024799
	O76062
	Q71KT5
	NM_001277233; NM_003273
	NM_028454
	NP_001264162; NP_003264
	NP_082730
	Wikidata
View/Edit Human	View/Edit Mouse

Delta(14)-sterol reductase is an enzyme that in humans is encoded by the TM7SF2 gene.