TMBIM1

TMBIM1
Identifiers
Aliases	TMBIM1, LFG3, MST100, MSTP100, RECS1, PP1201, transmembrane BAX inhibitor motif containing 1
External IDs	OMIM: 610364; MGI: 1916910; HomoloGene: 36404; GeneCards: TMBIM1; OMA:TMBIM1 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	218,292,586 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	74,344,781 bp
RNA expression pattern
	Top expressed in
	Descending thoracic aorta; ; ascending aorta; ; body of pancreas; ; body of stomach; ; gastric mucosa; ; right lung; ; gallbladder; ; skin of leg; ; skin of abdomen; ; popliteal artery;
	Top expressed in
	epithelium of stomach; ; pyloric antrum; ; vestibular membrane of cochlear duct; ; left colon; ; ankle; ; mucous cell of stomach; ; ascending aorta; ; aortic valve; ; carotid body; ; transitional epithelium of urinary bladder;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	death receptor binding;
Cellular component	integral component of membrane; lysosomal membrane; endosome; Golgi apparatus; lysosome; endosome membrane; extracellular exosome; membrane; plasma membrane; specific granule membrane; intracellular membrane-bounded organelle;
Biological process	negative regulation of Fas signaling pathway; positive regulation of blood vessel remodeling; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; negative regulation of catalytic activity; neutrophil degranulation; negative regulation of protein localization to plasma membrane;
	Sources:Amigo / QuickGO
Orthologs
	64114
	69660
	ENSG00000135926
	ENSMUSG00000006301
	Q969X1
	Q8BJZ3
NM_022152; NM_001321427; NM_001321428; NM_001321429; NM_001321430;
	NM_001321432; NM_001321433; NM_001321435; NM_001321436; NM_001321438
	NM_027154
NP_001308356; NP_001308357; NP_001308358; NP_001308359; NP_001308361;
	NP_001308362; NP_001308364; NP_001308365; NP_001308367; NP_071435
	NP_081430
	Wikidata
View/Edit Human	View/Edit Mouse

Transmembrane BAX inhibitor motif-containing protein 1 is a protein that in humans is encoded by the TMBIM1 gene.