TMC8

TMC8
Identifiers
Aliases	TMC8, EV2, EVER2, EVIN2, transmembrane channel like 8
External IDs	OMIM: 605829; MGI: 2669037; HomoloGene: 45126; GeneCards: TMC8; OMA:TMC8 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	78,142,968 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	117,683,936 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; spleen; ; appendix; ; lymph node; ; blood; ; thymus; ; mucosa of ileum; ; bone marrow cells; ; monocyte; ; superficial temporal artery;
	Top expressed in
	granulocyte; ; thymus; ; yolk sac; ; blood; ; morula; ; embryo; ; blastocyst; ; stomach; ; transitional epithelium of urinary bladder; ; tail of embryo;
	More reference expression data
	n/a
Gene ontology
Molecular function	signaling receptor binding; protein binding; ion channel activity; mechanosensitive ion channel activity;
Cellular component	cytoplasm; integral component of membrane; Golgi apparatus; nuclear membrane; extracellular exosome; endoplasmic reticulum membrane; endoplasmic reticulum; membrane; extracellular space; integral component of plasma membrane;
Biological process	negative regulation of protein oligomerization; regulation of extrinsic apoptotic signaling pathway via death domain receptors; zinc ion homeostasis; ion transport; negative regulation of protein binding; regulation of cell growth; transport; ion transmembrane transport; transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	147138
	217356
	ENSG00000167895
	ENSMUSG00000050106
	Q8IU68
	Q7TN58
	NM_152468
	NM_001195088; NM_001195089; NM_001195090; NM_181856
	NP_689681
	NP_001182017; NP_001182018; NP_001182019; NP_862904
	Wikidata
View/Edit Human	View/Edit Mouse

Transmembrane channel-like protein 8 is a protein which in humans is encoded by the TMC8 gene.