TMEM106A

TMEM106A
Identifiers
Aliases	TMEM106A, transmembrane protein 106A
External IDs	MGI: 1922056; HomoloGene: 16996; GeneCards: TMEM106A; OMA:TMEM106A - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	43,220,041 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	101,482,614 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; renal medulla; ; pylorus; ; synovial membrane; ; monocyte; ; tibia; ; bone marrow cells; ; gonad; ; appendix; ; parietal pleura;
	Top expressed in
	right kidney; ; lumbar spinal ganglion; ; human kidney; ; epithelium of small intestine; ; ileum; ; intestinal villus; ; stroma of bone marrow; ; proximal tubule; ; jejunum; ; duodenum;
	More reference expression data
	n/a
Gene ontology
Molecular function	molecular function;
Cellular component	integral component of membrane; membrane; plasma membrane;
Biological process	biological process; CD80 biosynthetic process; CD86 biosynthetic process; macrophage activation; positive regulation of I-kappaB kinase/NF-kappaB signaling; positive regulation of MAPK cascade; positive regulation of MHC class II biosynthetic process; positive regulation of nitric oxide metabolic process; immune system process; innate immune response;
	Sources:Amigo / QuickGO
Orthologs
	113277
	217203
	ENSG00000184988
	ENSMUSG00000034947
	Q96A25
	Q8VC04
	NM_001291586; NM_001291587; NM_001291588; NM_145041
	NM_144830; NM_001359325; NM_001359326; NM_001359327
	NP_001278515; NP_001278516; NP_001278517; NP_659478
	NP_659079; NP_001346254; NP_001346255; NP_001346256
	Wikidata
View/Edit Human	View/Edit Mouse

TMEM106A is a gene that encodes the transmembrane protein 106A (TMEM106A) in Homo sapiens. It is located at 17q21.31 on the plus strand next to cancer-related genes NBR1 and BRCA1. The TMEM106A gene contains a domain of unknown function, DUF1356.