TMEM106C

TMEM106C
Identifiers
Aliases	TMEM106C, transmembrane protein 106C
External IDs	MGI: 1196384; HomoloGene: 11440; GeneCards: TMEM106C; OMA:TMEM106C - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	47,968,878 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	97,868,156 bp
RNA expression pattern
	Top expressed in
	rectum; ; mucosa of transverse colon; ; mucosa of sigmoid colon; ; right lung; ; Descending thoracic aorta; ; islet of Langerhans; ; ascending aorta; ; body of pancreas; ; duodenum; ; right hemisphere of cerebellum;
	Top expressed in
	neural layer of retina; ; choroid plexus of fourth ventricle; ; spermatocyte; ; olfactory epithelium; ; transitional epithelium of urinary bladder; ; pituitary gland; ; Ileal epithelium; ; right kidney; ; lacrimal gland; ; adrenal gland;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; molecular function;
Cellular component	integral component of membrane; endoplasmic reticulum membrane; endoplasmic reticulum; membrane; cellular component;
Biological process	biological process;
	Sources:Amigo / QuickGO
Orthologs
	79022
	380967
	ENSG00000134291
	ENSMUSG00000052369
	Q9BVX2
	Q80VP8
NM_024056; NM_001143841; NM_001143842; NM_001143843; NM_001143844;
	NM_001143845
	NM_001252153; NM_201359; NM_001356508
	NP_001137313; NP_001137314; NP_001137315; NP_076961
	NP_001239082; NP_958747; NP_001343437
	Wikidata
View/Edit Human	View/Edit Mouse

TMEM106C is a gene that encodes the transmembrane protein 106C (TMEM106C) in Homo sapiens It has been found to be overexpressed in cancer cells and also is related to distal arthrogryposis, a condition of stiff joints and irregular muscle development. The TMEM106C gene contains a domain of unknown function, DUF1356, that spans most of the protein. Transmembrane protein 106C also goes by the aliases MGC5576 or MGC111210, LOC79022.