TMEM143

TMEM143 (Transmembrane protein 143) is a protein that in humans is encoded by TMEM143 gene. TMEM143, a dual-pass protein (two transmembrane domains), is predicted to reside in the mitochondria and high expression has been found in both human skeletal muscle and the heart. Interaction with other proteins indicate that TMEM143 could potentially play a role in tumor suppression/expression and cancer regulation.