TMEM38A

TMEM38A
Identifiers
Aliases	TMEM38A, TRIC-A, TRICA, transmembrane protein 38A
External IDs	OMIM: 611235; MGI: 1921416; HomoloGene: 11449; GeneCards: TMEM38A; OMA:TMEM38A - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	16,690,023 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	72,587,282 bp
RNA expression pattern
	Top expressed in
	muscle of thigh; ; gastrocnemius muscle; ; quadriceps femoris muscle; ; vastus lateralis muscle; ; skeletal muscle tissue; ; tibialis anterior muscle; ; Skeletal muscle tissue of rectus abdominis; ; deltoid muscle; ; biceps brachii; ; Skeletal muscle tissue of biceps brachii;
	Top expressed in
	interventricular septum; ; muscle of thigh; ; skeletal muscle tissue; ; medial head of gastrocnemius muscle; ; triceps brachii muscle; ; quadriceps femoris muscle; ; tibialis anterior muscle; ; temporal muscle; ; sternocleidomastoid muscle; ; vastus lateralis muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	potassium channel activity; cation channel activity; calcium-activated potassium channel activity;
Cellular component	sarcoplasmic reticulum; integral component of membrane; nuclear membrane; extracellular exosome; membrane; sarcoplasmic reticulum membrane; nucleus;
Biological process	potassium ion transport; ion transport; potassium ion transmembrane transport; transport; endoplasmic reticulum organization; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; protein homotrimerization; cellular response to caffeine;
	Sources:Amigo / QuickGO
Orthologs
	79041
	74166
	ENSG00000072954
	ENSMUSG00000031791
	Q9H6F2
	Q3TMP8
	NM_024074
	NM_144534
	NP_076979
	NP_653117; NP_001344207; NP_001344208; NP_001344209; NP_001344213
	Wikidata
View/Edit Human	View/Edit Mouse

Trimeric intracellular cation-selective channel A (TRIC-A) is a monovalent cation channel in the SR and nuclear membranes of skeletal muscle cells, encoded by the transmembrane protein 38A (TMEM38A) gene. It is one of two known TRIC proteins, the other being TRIC-B.