TMEM67

TMEM67
Identifiers
Aliases	TMEM67, JBTS6, MECKELIN, MKS3, NPHP11, TNEM67, transmembrane protein 67
External IDs	OMIM: 609884; MGI: 1923928; HomoloGene: 71886; GeneCards: TMEM67; OMA:TMEM67 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	93,819,234 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	12,090,020 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; right uterine tube; ; Achilles tendon; ; bronchial epithelial cell; ; olfactory zone of nasal mucosa; ; ventricular zone; ; left ventricle; ; anterior pituitary; ; gonad; ; left testis;
	Top expressed in
	spermatocyte; ; spermatid; ; tail of embryo; ; genital tubercle; ; neural layer of retina; ; ventricular zone; ; zygote; ; right kidney; ; primary visual cortex; ; lumbar subsegment of spinal cord;
	More reference expression data
	n/a
Gene ontology
Molecular function	unfolded protein binding; filamin binding; protein binding;
Cellular component	cytoplasm; integral component of membrane; centrosome; cell projection; MKS complex; endoplasmic reticulum membrane; membrane; plasma membrane; cilium; endoplasmic reticulum; ciliary membrane; cytoskeleton; cytoplasmic vesicle membrane; ciliary transition zone;
Biological process	negative regulation of centrosome duplication; cell projection organization; ubiquitin-dependent ERAD pathway; cilium assembly; ciliary basal body-plasma membrane docking;
	Sources:Amigo / QuickGO
Orthologs
	91147
	329795
	ENSG00000164953
	ENSMUSG00000049488
	Q5HYA8
	Q8BR76
	NM_001142301; NM_153704
	NM_177861
	NP_001135773; NP_714915
	NP_808529
	Wikidata
View/Edit Human	View/Edit Mouse

Meckelin is a protein that in humans is encoded by the TMEM67 gene.