TMPRSS3

TMPRSS3
Identifiers
Aliases	TMPRSS3, DFNB10, DFNB8, ECHOS1, TADG12, transmembrane protease, serine 3, transmembrane serine protease 3
External IDs	OMIM: 605511; MGI: 2155445; HomoloGene: 56985; GeneCards: TMPRSS3; OMA:TMPRSS3 - orthologs
Gene location (Human)
Chr.	Chromosome 21 (human)
End	42,396,091 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	31,417,951 bp
RNA expression pattern
	Top expressed in
	pancreatic ductal cell; ; right uterine tube; ; bronchial epithelial cell; ; mucosa of paranasal sinus; ; olfactory zone of nasal mucosa; ; pylorus; ; gallbladder; ; nasal epithelium; ; epithelium of nasopharynx; ; germinal epithelium;
	Top expressed in
	vestibular sensory epithelium; ; utricle; ; vestibular membrane of cochlear duct; ; cochlea; ; granulocyte; ; submandibular gland; ; parasympathetic nervous system; ; thyroid gland; ; pharynx; ; tongue;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	scavenger receptor activity; sodium channel regulator activity; peptidase activity; serine-type peptidase activity; hydrolase activity; serine-type endopeptidase activity;
Cellular component	integral component of membrane; soma; endoplasmic reticulum membrane; endoplasmic reticulum; membrane;
Biological process	cellular sodium ion homeostasis; hearing; receptor-mediated endocytosis; proteolysis; regulation of molecular function; vesicle-mediated transport; endocytosis;
	Sources:Amigo / QuickGO
Orthologs
	64699
	140765
	ENSG00000160183
	ENSMUSG00000024034
	P57727
	Q8K1T0
	NM_001256317; NM_024022; NM_032401; NM_032404; NM_032405
	NM_001163776; NM_080727
	NP_001243246; NP_076927; NP_115780; NP_115781
	NP_001157248; NP_542765
	Wikidata
View/Edit Human	View/Edit Mouse

Transmembrane protease, serine 3 is an enzyme that in humans is encoded by the TMPRSS3 gene.