The 2025 Sacrifice was a professional wrestling event produced by Total Nonstop Action Wrestling. The event took place on March 14, 2025, at the El Paso County Coliseum in El Paso, Texas, and aired on TNA+. It was the 16th event under the Sacrifice chronology. Wrestlers from WWE's NXT brand, with which TNA has a partnership, also appeared at the event. The reported attendance was approximately 3,500, making Sacrifice TNA's 2nd largest attended event in the United States in over ten years after January 19's Genesis pay-per-view.  
Ten matches were contested at the event, including one on the Countdown to Sacrifice pre-show. In the main event, Joe Hendry, Matt Hardy, Elijah, Leon Slater, and Nic Nemeth defeated The System (Eddie Edwards, Brian Myers, and JDC) and The Colóns (Eddie Colón and Orlando Colón) in a Steel Cage 10-man tag team match. In other prominent matches, Moose defeated Jeff Hardy in a Ladder match to retain the TNA X Division Championship, Masha Slamovich defeated NXT wrestler Cora Jade to retain the TNA Knockouts World Championship, and Ash by Elegance, Heather by Elegance, and The Personal Concierge defeated Spitfire (Dani Luna and Jody Threat) in a 2-on-3 Handicap match to win the TNA Knockouts World Tag Team Championship. The event was notable for the appearance of NXT wrestlers Lash Legend and Jakara Jackson from Meta-Four.