TNIP2

TNIP2
Identifiers
Aliases	TNIP2, ABIN2, FLIP1, KLIP, TNFAIP3 interacting protein 2
External IDs	OMIM: 610669; MGI: 2386643; HomoloGene: 11515; GeneCards: TNIP2; OMA:TNIP2 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	2,756,342 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	34,671,335 bp
RNA expression pattern
	Top expressed in
	tendon of biceps brachii; ; pancreatic ductal cell; ; granulocyte; ; mucosa of transverse colon; ; apex of heart; ; gastric mucosa; ; muscle layer of sigmoid colon; ; body of stomach; ; upper lobe of left lung; ; monocyte;
	Top expressed in
	neural layer of retina; ; interventricular septum; ; granulocyte; ; lip; ; right kidney; ; primary visual cortex; ; muscle of thigh; ; superior frontal gyrus; ; dentate gyrus of hippocampal formation granule cell; ; esophagus;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; protein kinase binding; metal ion binding; polyubiquitin modification-dependent protein binding; K63-linked polyubiquitin modification-dependent protein binding;
Cellular component	nucleus; cytosol; cytoplasm; nucleoplasm;
Biological process	negative regulation of endothelial cell apoptotic process; regulation of transcription, DNA-templated; CD40 signaling pathway; protein stabilization; positive regulation of macrophage activation; transcription, DNA-templated; stress-activated MAPK cascade; positive regulation of I-kappaB kinase/NF-kappaB signaling; positive regulation of B cell activation; inflammatory response; I-kappaB kinase/NF-kappaB signaling; positive regulation of transcription by RNA polymerase II; apoptotic process; toll-like receptor 9 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 3 signaling pathway; protein deubiquitination; cellular response to lipopolysaccharide; interleukin-1-mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	79155
	231130
	ENSG00000168884
	ENSMUSG00000059866
	Q8NFZ5
	Q99JG7
	NM_024309; NM_001161527; NM_001292016
	NM_139064
	NP_001154999; NP_001278945; NP_077285
	NP_620703
	Wikidata
View/Edit Human	View/Edit Mouse

TNFAIP3-interacting protein 2 is a protein that in humans is encoded by the TNIP2 gene. TNIP2 contains multiple amino acid sites that are phosphorylated and ubiquitinated.