TOMM22

TOMM22
Identifiers
Aliases	TOMM22, 1C9-2, MST065, MSTP065, TOM22, translocase of outer mitochondrial membrane 22
External IDs	OMIM: 607046; MGI: 2450248; HomoloGene: 10638; GeneCards: TOMM22; OMA:TOMM22 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	38,685,421 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	79,557,601 bp
RNA expression pattern
	Top expressed in
	tendon of biceps brachii; ; mucosa of transverse colon; ; rectum; ; ganglionic eminence; ; internal globus pallidus; ; monocyte; ; muscle of thigh; ; apex of heart; ; prefrontal cortex; ; granulocyte;
	Top expressed in
	spermatid; ; spermatocyte; ; morula; ; neural tube; ; epiblast; ; Mesencephalon; ; ileum; ; ganglionic eminence; ; ventricular zone; ; embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein transmembrane transporter activity; protein binding;
Cellular component	mitochondrial outer membrane translocase complex; integral component of membrane; mitochondrial inner membrane; mitochondrial outer membrane; integral component of mitochondrial outer membrane; membrane; mitochondrion;
Biological process	protein transport; protein targeting to mitochondrion; protein import into mitochondrial matrix; intracellular protein transport; protein insertion into mitochondrial outer membrane; macroautophagy; transport; positive regulation of apoptotic process; protein insertion into mitochondrial membrane; protein transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	56993
	223696
	ENSG00000100216
	ENSMUSG00000022427
	Q9NS69
	Q9CPQ3
	NM_020243
	NM_172609
	NP_064628
	NP_766197
	Wikidata
View/Edit Human	View/Edit Mouse

Mitochondrial import receptor subunit TOM22 homolog (hTom22) is a protein that in humans is encoded by the TOMM22 gene.

The protein encoded by this gene is an integral membrane protein of the outer mitochondrial membrane. The encoded protein interacts with TOMM20 and TOMM40, and with other proteins forms a complex – the translocase of the outer membrane, to import cytosolic preproteins into the mitochondrion.