TP53INP1

TP53INP1
Identifiers
Aliases	TP53INP1, SIP, TP53DINP1, TP53INP1A, TP53INP1B, Teap, p53DINP1, tumor protein p53 inducible nuclear protein 1
External IDs	OMIM: 606185; MGI: 1926609; HomoloGene: 11065; GeneCards: TP53INP1; OMA:TP53INP1 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	94,949,378 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	11,174,379 bp
RNA expression pattern
	Top expressed in
	sperm; ; epithelium of nasopharynx; ; thymus; ; bronchial epithelial cell; ; mucosa of ileum; ; body of pancreas; ; visceral pleura; ; parietal pleura; ; germinal epithelium; ; palpebral conjunctiva;
	Top expressed in
	stroma of bone marrow; ; lymph node; ; thymus; ; mesenteric lymph nodes; ; Paneth cell; ; vestibular membrane of cochlear duct; ; ascending aorta; ; utricle; ; blood; ; pituitary gland;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	antioxidant activity; protein binding;
Cellular component	cytosol; PML body; autophagosome; cytoplasmic vesicle; nucleus; nucleoplasm; cytoplasm;
Biological process	regulation of transcription, DNA-templated; cellular response to ethanol; positive regulation of autophagy; cellular response to methyl methanesulfonate; cellular response to UV; cellular oxidant detoxification; positive regulation of apoptotic signaling pathway; response to heat; autophagosome assembly; transcription, DNA-templated; cellular response to hydroperoxide; positive regulation of transcription, DNA-templated; autophagy; negative regulation of cell migration; regulation of autophagy; positive regulation of apoptotic process; autophagic cell death; negative regulation of cell population proliferation; apoptotic process; regulation of apoptotic process; regulation of signal transduction by p53 class mediator; positive regulation of gene expression; negative regulation of gene expression; negative regulation of fibroblast proliferation; negative regulation of myofibroblast differentiation;
	Sources:Amigo / QuickGO
Orthologs
	94241
	60599
	ENSG00000164938
	ENSMUSG00000028211
	Q96A56
	Q9QXE4
	NM_001135733; NM_033285
	NM_001199105; NM_021897
	NP_001129205; NP_150601
	NP_001186034; NP_068697
	Wikidata
View/Edit Human	View/Edit Mouse

Tumor protein p53-inducible nuclear protein 1 is a protein that in humans is encoded by the TP53INP1 gene. In mice this protein is also called TRP53INP1 and is encoded by the Trp53inp1 gene. The protein is also referred to as SIP or "stress inducible protein".