TRAM2

TRAM2
Identifiers
Aliases	TRAM2, translocation associated membrane protein 2
External IDs	OMIM: 608485; MGI: 1924817; HomoloGene: 8183; GeneCards: TRAM2; OMA:TRAM2 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	52,577,060 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	21,149,453 bp
RNA expression pattern
	Top expressed in
	oocyte; ; secondary oocyte; ; stromal cell of endometrium; ; placenta; ; cartilage tissue; ; tibia; ; synovial membrane; ; synovial joint; ; mucosa of ileum; ; visceral pleura;
	Top expressed in
	ascending aorta; ; aortic valve; ; cumulus cell; ; calvaria; ; body of femur; ; mesenteric lymph nodes; ; umbilical cord; ; endothelial cell of lymphatic vessel; ; tail of embryo; ; ankle;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	membrane; integral component of membrane; rough endoplasmic reticulum;
Biological process	protein transport; collagen biosynthetic process; protein insertion into ER membrane; SRP-dependent cotranslational protein targeting to membrane, translocation;
	Sources:Amigo / QuickGO
Orthologs
	9697
	170829
	ENSG00000065308
	ENSMUSG00000041779
	Q15035
	Q924Z5
	NM_012288
	NM_177409
	NP_036420
	NP_803128
	Wikidata
View/Edit Human	View/Edit Mouse

Translocating chain-associated membrane protein 2 is a protein that in humans is encoded by the TRAM2 gene.

TRAM2 is a component of the translocon, a gated macromolecular channel that controls the posttranslational processing of nascent secretory and membrane proteins at the endoplasmic reticulum (ER) membrane.