TRAPPC10

TRAPPC10
Identifiers
Aliases	TRAPPC10, EHOC-1, EHOC1, GT334, TMEM1, TRS130, TRS30, trafficking protein particle complex 10, trafficking protein particle complex subunit 10
External IDs	OMIM: 602103; MGI: 1336209; HomoloGene: 37751; GeneCards: TRAPPC10; OMA:TRAPPC10 - orthologs
Gene location (Human)
Chr.	Chromosome 21 (human)
End	44,106,552 bp
RNA expression pattern
	Top expressed in
	bone marrow cells; ; granulocyte; ; rectum; ; appendix; ; monocyte; ; stromal cell of endometrium; ; epithelium of colon; ; transverse colon; ; sural nerve; ; islet of Langerhans;
	n/a
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	sodium ion transmembrane transporter activity; protein binding;
Cellular component	integral component of membrane; cytosol; Golgi apparatus; TRAPPII protein complex; Golgi membrane; TRAPP complex;
Biological process	early endosome to Golgi transport; COPII vesicle coating; intra-Golgi vesicle-mediated transport; vesicle-mediated transport; sodium ion transport; sodium ion transmembrane transport; protein complex oligomerization;
	Sources:Amigo / QuickGO
Orthologs
	7109
	216131
	ENSG00000160218
	ENSMUSG00000000374
	P48553
	Q3TLI0
	NM_001001723; NM_003274; NM_001351709
	NM_001081055
	NP_003265; NP_001338638
	NP_001074524
	Wikidata
View/Edit Human	View/Edit Mouse

Trafficking protein particle complex subunit 10 is a protein that in humans is encoded by the TRAPPC10 gene.

The protein encoded by this gene is a transmembrane protein found in the cis-Golgi complex. The encoded protein is part of the multisubunit transport protein particle (TRAPP) complex and may be involved in vesicular transport from the endoplasmic reticulum to the Golgi.

Mutations in this gene could be responsible for the Unverricht-Lundborg type of progressive myoclonus epilepsy, or for autoimmune polyglandular disease type 1. Two transcript variants encoding different isoforms have been found for this gene.