TRIM15

TRIM15
Identifiers
Aliases	TRIM15, RNF93, ZNF178, ZNFB7, tripartite motif containing 15
External IDs	MGI: 1916347; HomoloGene: 23819; GeneCards: TRIM15; OMA:TRIM15 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	30,172,693 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	37,178,102 bp
RNA expression pattern
	Top expressed in
	duodenum; ; mucosa of transverse colon; ; rectum; ; right lobe of liver; ; gallbladder; ; human kidney; ; appendix; ; epithelium of colon; ; smooth muscle tissue; ; islet of Langerhans;
	Top expressed in
	intestinal villus; ; ileum; ; jejunum; ; primary oocyte; ; epithelium of small intestine; ; duodenum; ; secondary oocyte; ; zygote; ; yolk sac; ; embryo;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	zinc ion binding; protein binding; metal ion binding;
Cellular component	intracellular anatomical structure;
Biological process	mesodermal cell fate determination; positive regulation of DNA-binding transcription factor activity; innate immune response; positive regulation of RIG-I signaling pathway; positive regulation of NF-kappaB transcription factor activity; positive regulation of type I interferon production; negative regulation of intracellular transport of viral material;
	Sources:Amigo / QuickGO
Orthologs
	89870
	69097
ENSG00000235960; ENSG00000227147; ENSG00000233599; ENSG00000204610; ENSG00000224145;
	ENSG00000235905; ENSG00000137384; ENSG00000235259
	ENSMUSG00000050747
	Q9C019
	n/a
	NM_033229; NM_052812
	NM_001024134; NM_001177872
	NP_150232
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Tripartite motif-containing protein 15 is a protein that in humans is encoded by the TRIM15 gene.

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. Its function has not been identified. Alternate splicing of this gene results in two transcript variants encoding different isoforms.