TRIM24

TRIM24
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2YYN, 3O33, 3O34, 3O35, 3O36, 3O37, 4YAB, 4YAD, 4YAT, 4YAX, 4YBM, 4YBS, 4YBT, 4YC9, 4ZQL
Identifiers
Aliases	TRIM24, PTC6, RNF82, TF1A, TIF1, TIF1A, TIF1ALPHA, hTIF1, tripartite motif containing 24
External IDs	OMIM: 603406; MGI: 109275; HomoloGene: 20830; GeneCards: TRIM24; OMA:TRIM24 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	138,589,996 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	37,943,231 bp
RNA expression pattern
	Top expressed in
	sperm; ; ganglionic eminence; ; ventricular zone; ; right adrenal cortex; ; parotid gland; ; left adrenal gland; ; endothelial cell; ; left adrenal cortex; ; gonad; ; Skeletal muscle tissue of biceps brachii;
	Top expressed in
	zygote; ; secondary oocyte; ; spermatid; ; spermatocyte; ; genital tubercle; ; seminiferous tubule; ; tail of embryo; ; primary oocyte; ; lacrimal gland; ; parotid gland;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein kinase activity; sequence-specific DNA binding; DNA binding; ubiquitin protein ligase activity; transcription coactivator activity; zinc ion binding; p53 binding; chromatin binding; metal ion binding; ubiquitin-protein transferase activity; methylated histone binding; estrogen response element binding; protein binding; nuclear receptor binding; lysine-acetylated histone binding; signaling receptor binding; protein tyrosine kinase activity; transferase activity;
Cellular component	cytoplasm; cytosol; intracellular anatomical structure; perichromatin fibrils; nucleus; nucleoplasm;
Biological process	regulation of apoptotic process; regulation of transcription, DNA-templated; regulation of protein stability; calcium ion homeostasis; regulation of signal transduction by p53 class mediator; regulation of vitamin D receptor signaling pathway; transcription by RNA polymerase II; transcription, DNA-templated; cellular response to estrogen stimulus; positive regulation of transcription, DNA-templated; protein phosphorylation; positive regulation of gene expression; protein catabolic process; protein ubiquitination; protein autophosphorylation; negative regulation of transcription, DNA-templated; negative regulation of cell population proliferation; peptidyl-tyrosine phosphorylation;
	Sources:Amigo / QuickGO
Orthologs
	8805
	21848
	ENSG00000122779
	ENSMUSG00000029833
	O15164
	Q64127
	NM_003852; NM_015905
	NM_001272064; NM_001272076; NM_145076
	NP_003843; NP_056989
	NP_001258993; NP_001259005; NP_659542
	Wikidata
View/Edit Human	View/Edit Mouse

Tripartite motif-containing 24 (TRIM24) also known as transcriptional intermediary factor 1α (TIF1α) is a protein that, in humans, is encoded by the TRIM24 gene.