TRIM37

TRIM37
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3LRQ
Identifiers
Aliases	TRIM37, MUL, POB1, TEF3, tripartite motif containing 37
External IDs	OMIM: 605073; MGI: 2153072; HomoloGene: 9084; GeneCards: TRIM37; OMA:TRIM37 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	59,106,921 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	87,111,509 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; secondary oocyte; ; sperm; ; Brodmann area 23; ; middle temporal gyrus; ; postcentral gyrus; ; Pons; ; Brodmann area 46; ; superior frontal gyrus; ; frontal pole;
	Top expressed in
	spermatocyte; ; spermatid; ; medial vestibular nucleus; ; pontine nuclei; ; primary motor cortex; ; deep cerebellar nuclei; ; medial dorsal nucleus; ; inferior colliculi; ; seminiferous tubule; ; central gray substance of midbrain;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein homodimerization activity; ubiquitin protein ligase activity; zinc ion binding; chromatin binding; metal ion binding; ubiquitin-protein transferase activity; protein binding; tumor necrosis factor receptor binding; ubiquitin protein ligase binding; transferase activity;
Cellular component	cytosol; ESC/E(Z) complex; intracellular anatomical structure; aggresome; perinuclear region of cytoplasm; peroxisome; cytoplasm;
Biological process	negative regulation of centriole replication; positive regulation of DNA-binding transcription factor activity; negative regulation of transcription by RNA polymerase II; transcription, DNA-templated; positive regulation of NF-kappaB transcription factor activity; protein ubiquitination; negative regulation of NF-kappaB transcription factor activity; aggresome assembly; protein autoubiquitination; histone H2A monoubiquitination; histone H2A-K119 monoubiquitination;
	Sources:Amigo / QuickGO
Orthologs
	4591
	68729
	ENSG00000108395
	ENSMUSG00000018548
	O94972
	Q6PCX9
NM_001005207; NM_015294; NM_001320987; NM_001320988; NM_001320989;
	NM_001320990; NM_001353082; NM_001353083; NM_001353084; NM_001353085; NM_001353086
	NM_197987; NM_001363025; NM_001363026; NM_001363027; NM_001363028
NP_001005207; NP_001307916; NP_001307917; NP_001307918; NP_001307919;
	NP_056109; NP_001340011; NP_001340012; NP_001340013; NP_001340014; NP_001340015
	NP_932104; NP_001349954; NP_001349955; NP_001349956; NP_001349957
	Wikidata
View/Edit Human	View/Edit Mouse

Tripartite motif-containing protein 37 is an E3 ubiquitin ligase in humans that is encoded by the TRIM37 gene.