TRIM45

TRIM45
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2DS4
Identifiers
Aliases	TRIM45, RNF99, tripartite motif containing 45
External IDs	OMIM: 609318; MGI: 1918187; HomoloGene: 11865; GeneCards: TRIM45; OMA:TRIM45 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	117,122,587 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	100,844,236 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; right uterine tube; ; apex of heart; ; testicle; ; muscle of thigh; ; gastrocnemius muscle; ; right auricle of heart; ; gonad; ; tibialis anterior muscle; ; deltoid muscle;
	Top expressed in
	otolith organ; ; utricle; ; vestibular sensory epithelium; ; olfactory system; ; olfactory epithelium; ; seminiferous tubule; ; internal carotid artery; ; external carotid artery; ; spermatid; ; Jacobson's organ;
	More reference expression data
	n/a
Gene ontology
Molecular function	zinc ion binding; metal ion binding;
Cellular component	intracellular anatomical structure; nucleus; nucleoplasm; intercellular bridge; cytoplasm; cytosol;
Biological process	bone development;
	Sources:Amigo / QuickGO
Orthologs
	80263
	229644
	ENSG00000134253
	ENSMUSG00000033233
	Q9H8W5
	Q6PFY8
	NM_001145635; NM_025188
	NM_001165952; NM_001165953; NM_194343
	NP_001139107; NP_079464
	NP_001159424; NP_001159425; NP_919324
	Wikidata
View/Edit Human	View/Edit Mouse

tripartite motif containing 45, also known as TRIM45, is a human gene.

This gene encodes a member of the tripartite motif family. The encoded protein may function as a [transcriptional repressor of the mitogen-activated protein kinase pathway. Alternatively spliced transcript variants have been described.