TRIT1

TRIT1
Identifiers
Aliases	TRIT1, IPT, MOD5, GRO1, IPPT, IPTase, hGRO1, tRNA isopentenyltransferase 1, COXPD35
External IDs	OMIM: 617840; MGI: 1914216; HomoloGene: 7010; GeneCards: TRIT1; OMA:TRIT1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	39,883,511 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	122,948,742 bp
RNA expression pattern
	Top expressed in
	oocyte; ; body of pancreas; ; skin of leg; ; vagina; ; skin of abdomen; ; right uterine tube; ; secondary oocyte; ; left lobe of thyroid gland; ; prostate; ; body of uterus;
	Top expressed in
	saccule; ; medullary collecting duct; ; otic vesicle; ; renal corpuscle; ; otic placode; ; lacrimal gland; ; hair follicle; ; cumulus cell; ; primary oocyte; ; fossa;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; ATP binding; metal ion binding; tRNA dimethylallyltransferase activity; nucleic acid binding; zinc ion binding;
Cellular component	cytoplasm; mitochondrial matrix; mitochondrion; cellular component;
Biological process	mitochondrial tRNA modification; tRNA processing; tRNA modification;
	Sources:Amigo / QuickGO
Orthologs
	54802
	66966
	ENSG00000043514
	ENSMUSG00000028653
	Q9H3H1
	Q80UN9
	NM_001312691; NM_001312692; NM_017646
	NM_025873
	NP_001299620; NP_001299621; NP_060116
	NP_080149
	Wikidata
View/Edit Human	View/Edit Mouse

tRNA isopentenyltransferase, mitochondrial is an enzyme that in humans is encoded by the TRIT1 gene.

It catalyzes the addition of an isopentenyl group from dimethylallyl diphosphate (DMAPP) onto adenosine residue 37 of certain tRNA molecules.