TRNT1

TRNT1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1OU5, 4X4W
Identifiers
Aliases	TRNT1, CCA1, MtCCA, CGI-47, SIFD, tRNA nucleotidyl transferase 1, RPEM
External IDs	OMIM: 612907; MGI: 1917297; HomoloGene: 9333; GeneCards: TRNT1; OMA:TRNT1 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	3,150,879 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	106,759,435 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; secondary oocyte; ; gonad; ; Achilles tendon; ; parietal pleura; ; epithelium of colon; ; pancreatic epithelial cell; ; cartilage tissue; ; metanephros; ; testicle;
	Top expressed in
	spermatocyte; ; zygote; ; spermatid; ; genital tubercle; ; secondary oocyte; ; tail of embryo; ; yolk sac; ; ventricular zone; ; embryo; ; atrioventricular valve;
	More reference expression data
	n/a
Gene ontology
Molecular function	CTP:3'-cytidine-tRNA cytidylyltransferase activity; transferase activity; nucleotide binding; tRNA binding; nucleotidyltransferase activity; ATP binding; CTP:tRNA cytidylyltransferase activity; RNA binding; 5'-3' RNA polymerase activity; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity;
Cellular component	mitochondrial matrix; intracellular anatomical structure; mitochondrion; nucleoplasm;
Biological process	RNA processing; tRNA 3'-terminal CCA addition; tRNA processing; tRNA 3'-end processing; mitochondrial tRNA 3'-end processing;
	Sources:Amigo / QuickGO
Orthologs
	51095
	70047
	ENSG00000072756
	ENSMUSG00000013736
	Q96Q11
	Q8K1J6
	NM_001302946; NM_016000; NM_182916
	NM_001242358; NM_001242360; NM_027296
	NP_001289875; NP_886552; NP_001354250; NP_001354251; NP_001354252
	NP_001229287; NP_001229289; NP_081572
	Wikidata
View/Edit Human	View/Edit Mouse

tRNA-nucleotidyltransferase 1, is an enzyme that in humans is encoded by the TRNT1 gene. This enzyme adds the nucleotide sequence CCA to the 3' end of tRNA, using ATP and CTP as substrates. The sequence creates the binding site for an amino acid.