TRPC5

TRPC5
Identifiers
Aliases	TRPC5, PPP1R159, TRP5, transient receptor potential cation channel subfamily C member 5
External IDs	OMIM: 300334; MGI: 109524; HomoloGene: 74915; GeneCards: TRPC5; OMA:TRPC5 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	112,082,776 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	143,471,176 bp
RNA expression pattern
	Top expressed in
	testicle; ; gonad; ; prefrontal cortex; ; gastric mucosa; ; ganglionic eminence; ; liver; ; Brodmann area 9; ; primary visual cortex; ; Hypothalamus; ; right lobe of liver;
	Top expressed in
	supraoptic nucleus; ; lumbar subsegment of spinal cord; ; dentate gyrus of hippocampal formation granule cell; ; zygote; ; lateral hypothalamus; ; primary visual cortex; ; ventromedial nucleus; ; superior frontal gyrus; ; secondary oocyte; ; dorsomedial hypothalamic nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	inositol 1,4,5 trisphosphate binding; ion channel activity; store-operated calcium channel activity; protein binding; calcium channel activity; clathrin binding; actin binding; actinin binding; ATPase binding;
Cellular component	integral component of membrane; plasma membrane; integral component of plasma membrane; calcium channel complex; membrane; cytoplasm; growth cone; soma; dendrite; membrane raft; cation channel complex;
Biological process	manganese ion transport; ion transport; regulation of cytosolic calcium ion concentration; calcium ion transmembrane transport; calcium ion transport; nervous system development; regulation of membrane hyperpolarization; positive regulation of peptidyl-threonine phosphorylation; positive regulation of axon extension; positive regulation of cell population proliferation; positive regulation of cytosolic calcium ion concentration; neuron differentiation; positive regulation of neuron differentiation; negative regulation of dendrite morphogenesis; transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	7224
	22067
	ENSG00000072315
	ENSMUSG00000041710
	Q9UL62
	Q9QX29
	NM_012471
	NM_009428
	NP_036603
	NP_033454
	Wikidata
View/Edit Human	View/Edit Mouse

Short transient receptor potential channel 5 (TrpC5) also known as transient receptor protein 5 (TRP-5) is a protein that in humans is encoded by the TRPC5 gene. TrpC5 is subtype of the TRPC family of mammalian transient receptor potential ion channels.