TRPM6

TRPM6

Identifiers

TRPM6, CHAK2, HMGX, HOMG, HOMG1, HSH, transient receptor potential cation channel subfamily M member 6

External IDs

OMIM: 607009; MGI: 2675603; HomoloGene: 9767; GeneCards: TRPM6; OMA:TRPM6 - orthologs

Gene location (Human)

Chr.	Chromosome 9 (human)

Band	9q21.13	Start	74,722,495 bp
Band	9q21.13	End	74,888,094 bp

Gene location (Mouse)

Chr.	Chromosome 19 (mouse)

Band	19\|19 B	Start	18,727,347 bp
Band	19\|19 B	End	18,869,875 bp

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

mucosa of colon

mucosa of sigmoid colon

jejunal mucosa

rectum

mucosa of transverse colon

hair follicle

duodenum

testicle

gonad

gingival epithelium

Top expressed in

conjunctival fornix

left colon

spermatid

right lung lobe

seminiferous tubule

zygote

right kidney

oocyte

secondary oocyte

Paneth cell

More reference expression data


More reference expression data

Gene ontology
Molecular function	transferase activity nucleotide binding metal ion binding kinase activity protein serine/threonine kinase activity ion channel activity protein binding cation channel activity ATP binding calcium channel activity
Cellular component	integral component of membrane membrane plasma membrane brush border membrane apical plasma membrane
Biological process	phosphorylation metal ion transport cation transport ion transport protein tetramerization protein phosphorylation calcium ion transmembrane transport response to toxic substance calcium ion transport transmembrane transport
Sources:Amigo / QuickGO

Species

Human

Mouse


140803


225997


ENSG00000119121


ENSMUSG00000024727


Q9BX84


Q8CIR4

RefSeq (mRNA)


NM_001177310 NM_001177311 NM_017662


NM_153417

RefSeq (protein)


NP_001170781 NP_001170782 NP_060132


NP_700466

Location (UCSC)

Chr 9: 74.72 – 74.89 Mb

Chr 19: 18.73 – 18.87 Mb

PubMed search

View/Edit Human

View/Edit Mouse

TRPM6 is a transient receptor potential ion channel associated with hypomagnesemia with secondary hypocalcemia.